Individual islet respirometry reveals functional diversity within the islet population of mice and human donors

OBJECTIVE: Islets from the same pancreas show remarkable variability in glucose sensitivity. While mitochondrial respiration is essential for glucose-stimulated insulin secretion, little is known regarding heterogeneity in mitochondrial function at the individual islet level. This is due in part to...

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Dades bibliogràfiques
Publicat a:Mol Metab
Autors principals: Taddeo, Evan P., Stiles, Linsey, Sereda, Samuel, Ritou, Eleni, Wolf, Dane M., Abdullah, Muhamad, Swanson, Zachary, Wilhelm, Josh, Bellin, Melena, McDonald, Patrick, Caradonna, Kacey, Neilson, Andrew, Liesa, Marc, Shirihai, Orian S.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157638/
https://ncbi.nlm.nih.gov/pubmed/30098928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.07.003
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