The endothelial glycocalyx anchors von Willebrand factor fibers to the vascular endothelium

The dynamic change from a globular conformation to an elongated fiber determines the ability of von Willebrand factor (VWF) to trap platelets. Fiber formation is favored by the anchorage of VWF to the endothelial cell surface, and VWF-platelet aggregates on the endothelium contribute to inflammation...

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Bibliografische gegevens
Gepubliceerd in:Blood Adv
Hoofdauteurs: Kalagara, Thejaswi, Moutsis, Tracy, Yang, Yi, Pappelbaum, Karin I., Farken, Anne, Cladder-Micus, Lucia, Vidal-y-Sy, Sabine, John, Axel, Bauer, Alexander T., Moerschbacher, Bruno M., Schneider, Stefan W., Gorzelanny, Christian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2018
Onderwerpen:
Thrombosis and Hemostasis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156889/
https://ncbi.nlm.nih.gov/pubmed/30237293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017013995
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