The endothelial glycocalyx anchors von Willebrand factor fibers to the vascular endothelium

The dynamic change from a globular conformation to an elongated fiber determines the ability of von Willebrand factor (VWF) to trap platelets. Fiber formation is favored by the anchorage of VWF to the endothelial cell surface, and VWF-platelet aggregates on the endothelium contribute to inflammation...

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Vydáno v:Blood Adv
Hlavní autoři: Kalagara, Thejaswi, Moutsis, Tracy, Yang, Yi, Pappelbaum, Karin I., Farken, Anne, Cladder-Micus, Lucia, Vidal-y-Sy, Sabine, John, Axel, Bauer, Alexander T., Moerschbacher, Bruno M., Schneider, Stefan W., Gorzelanny, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2018
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156889/
https://ncbi.nlm.nih.gov/pubmed/30237293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017013995
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