Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease

This phase 3 trial evaluated the safety and hemostatic efficacy of a recombinant von Willebrand factor (rVWF) for treatment of bleeds in severe von Willebrand disease (VWD). rVWF was initially administered together with recombinant factor VIII (rFVIII) and subsequently alone, as long as hemostatic f...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Gill, Joan C., Castaman, Giancarlo, Windyga, Jerzy, Kouides, Peter, Ragni, Margaret, Leebeek, Frank W. G., Obermann-Slupetzky, Ortrun, Chapman, Miranda, Fritsch, Sandor, Pavlova, Borislava G., Presch, Isabella, Ewenstein, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616237/
https://ncbi.nlm.nih.gov/pubmed/26239086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-629873
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