Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging

Aging is characterized by a gradual functional decline of tissues with age. Adult stem and progenitor cells are responsible for tissue maintenance, repair, and regeneration, but during aging, this population of cells is decreased or its activity is reduced, compromising tissue integrity and causing...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Vilas, Jéssica M., Carneiro, Carmen, Da Silva‐Álvarez, Sabela, Ferreirós, Alba, González, Patricia, Gómez, María, Ortega, Sagrario, Serrano, Manuel, García‐Caballero, Tomás, González‐Barcia, Miguel, Vidal, Anxo, Collado, Manuel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Short Take
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156495/
https://ncbi.nlm.nih.gov/pubmed/30129215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12834
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