Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins

Cellular reprogramming to iPSCs has uncovered unsuspected links between tumor suppressors and pluripotency factors. Using this system, it was possible to identify tumor suppressor p27 as a repressor of Sox2 during differentiation. This led to the demonstration that defects in the repression of Sox2...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Vilas, Jéssica M., Ferreirós, Alba, Carneiro, Carmen, Morey, Lluis, Silva-Álvarez, Sabela Da, Fernandes, Tânia, Abad, María, Croce, Luciano Di, García-Caballero, Tomás, Serrano, Manuel, Rivas, Carmen, Vidal, Anxo, Collado, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413632/
https://ncbi.nlm.nih.gov/pubmed/25576924
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