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Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging
Aging is characterized by a gradual functional decline of tissues with age. Adult stem and progenitor cells are responsible for tissue maintenance, repair, and regeneration, but during aging, this population of cells is decreased or its activity is reduced, compromising tissue integrity and causing...
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| Pubblicato in: | Aging Cell |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156495/ https://ncbi.nlm.nih.gov/pubmed/30129215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12834 |
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