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Cryo-EM structure of a mitochondrial calcium uniporter

Calcium transport plays an important role in regulating mitochondrial physiology and pathophysiology. The mitochondrial calcium uniporter (MCU) is a calcium-selective ion channel that is the primary mediator for calcium uptake into the mitochondrial matrix. Here we present the cryo-electron microsco...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Science
Prif Awduron: Yoo, Jiho, Wu, Mengyu, Yin, Ying, Herzik, Mark A., Lander, Gabriel C., Lee, Seok-Yong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155975/
https://ncbi.nlm.nih.gov/pubmed/29954988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar4056
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