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X-ray and cryo-EM structures of the mitochondrial calcium uniporter
Mitochondrial calcium uptake plays critical roles in regulating ATP production, intracellular calcium signaling, and cell death. This uptake is mediated by a highly selective calcium channel called the mitochondrial calcium uniporter. Here, we determined the structures of the pore-forming MCU protei...
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| Publicado en: | Nature |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6368340/ https://ncbi.nlm.nih.gov/pubmed/29995856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0330-9 |
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