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Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters

The mitochondrial calcium uniporter (MCU) is a highly selective calcium channel and a major route of calcium entry into mitochondria. How the channel catalyses ion permeation and achieves ion selectivity are not well understood, partly because MCU is thought to have a distinct architecture in compar...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Baradaran, Rozbeh, Wang, Chongyuan, Siliciano, Andrew Francis, Long, Stephen Barstow
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336196/
https://ncbi.nlm.nih.gov/pubmed/29995857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0331-8
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