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Cryo-EM structure of the mitochondrial calcium uniporter

The mitochondrial calcium uniporter is a highly selective calcium channel localized to the inner mitochondrial membrane. Here, we describe the structure of an MCU ortholog from the fungus Neosartorya fischeri (NfMCU) determined to 3.8 Å resolution by phase-plate cryo-electron microscopy. The channel...

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Publicat a:Nature
Autors principals: Nguyen, Nam X., Armache, Jean-Paul, Lee, Changkeun, Yang, Yi, Zeng, Weizhong, Mootha, Vamsi K., Cheng, Yifan, Bai, Xiao-chen, Jiang, Youxing
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063787/
https://ncbi.nlm.nih.gov/pubmed/29995855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0333-6
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