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Structural mechanism of EMRE-dependent gating of the human mitochondrial calcium uniporter
Mitochondrial calcium uptake is crucial to the regulation of eukaryotic Ca(2+) homeostasis and is mediated by the mitochondria calcium uniporter (MCU). While MCU alone can transport Ca(2+) in primitive eukaryotes, metazoans require an essential single membrane-spanning auxiliary component called EMR...
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| Publicado no: | Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6597010/ https://ncbi.nlm.nih.gov/pubmed/31080062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.03.050 |
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