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Cearoin Induces Autophagy, ERK Activation and Apoptosis via ROS Generation in SH-SY5Y Neuroblastoma Cells

Neuroblastomas are the most common solid extracranial tumors in childhood. We investigated the anticancer effect of cearoin isolated from Dalbergia odorifera in human neuroblastoma SH-SY5Y cells. SH-SY5Y cells were treated with various doses of cearoin. The viability was measured by MTT assay. DCFDA...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Bastola, Tonking, An, Ren-bo, Kim, Youn-Chul, Kim, Jaehyo, Seo, Jungwon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155915/
https://ncbi.nlm.nih.gov/pubmed/28178193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22020242
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