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ROS Production and ERK Activity Are Involved in the Effects of d-β-Hydroxybutyrate and Metformin in a Glucose Deficient Condition

Hypoglycemia, a complication of insulin or sulfonylurea therapy in diabetic patients, leads to brain damage. Furthermore, glucose replenishment following hypoglycemic coma induces neuronal cell death. In this study, we investigated the molecular mechanism underlying glucose deficiency-induced cytoto...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Lamichhane, Santosh, Bastola, Tonking, Pariyar, Ramesh, Lee, Eun-Sol, Lee, Ho-Sub, Lee, Dae Ho, Seo, Jungwon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372684/
https://ncbi.nlm.nih.gov/pubmed/28335557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030674
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