Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity

Scanning probe microscopy provides a unique window into the morphology, mechanics, and structure of proteins and their complexes on the nanoscale. Such measurements require, however, deposition of samples onto substrates. This process can affect conformations and assembly states of the molecular spe...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ruggeri, Francesco Simone, Charmet, Jerome, Kartanas, Tadas, Peter, Quentin, Chia, Sean, Habchi, Johnny, Dobson, Christopher M., Vendruscolo, Michele, Knowles, Tuomas P. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155325/
https://ncbi.nlm.nih.gov/pubmed/30250131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06345-4
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