Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity

Scanning probe microscopy provides a unique window into the morphology, mechanics, and structure of proteins and their complexes on the nanoscale. Such measurements require, however, deposition of samples onto substrates. This process can affect conformations and assembly states of the molecular spe...

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Foilsithe in:Nat Commun
Main Authors: Ruggeri, Francesco Simone, Charmet, Jerome, Kartanas, Tadas, Peter, Quentin, Chia, Sean, Habchi, Johnny, Dobson, Christopher M., Vendruscolo, Michele, Knowles, Tuomas P. J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155325/
https://ncbi.nlm.nih.gov/pubmed/30250131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06345-4
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