BRWD1 orchestrates epigenetic landscape of late B lymphopoiesis

Transcription factor (TF) networks determine cell fate in hematopoiesis. However, how TFs cooperate with other regulatory mechanisms to instruct transcription remains poorly understood. Here we show that in small pre-B cells, the lineage restricted epigenetic reader BRWD1 closes early development en...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mandal, Malay, Maienschein-Cline, Mark, Maffucci, Patrick, Veselits, Margaret, Kennedy, Domenick E., McLean, Kaitlin C., Okoreeh, Michael K., Karki, Sophiya, Cunningham-Rundles, Charlotte, Clark, Marcus R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155124/
https://ncbi.nlm.nih.gov/pubmed/30250168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06165-6
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