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Balancing Proliferation with Igκ Recombination during B-lymphopoiesis
The essential events of B-cell development are the stochastic and sequential rearrangement of immunoglobulin heavy (Igμ) and then light chain (Igκ followed by Igλ) loci. The counterpoint to recombination is proliferation, which both maintains populations of pro-B cells undergoing Igμ recombination a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3980108/ https://ncbi.nlm.nih.gov/pubmed/24765092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00139 |
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