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Ras orchestrates cell cycle exit and light chain recombination during early B cell development
Signals through the pre-B cell antigen receptor (pre-BCR) and IL-7 receptor (IL-7R) coordinate pre-B cell expansion with subsequent Igκ recombination. While many downstream effectors of each receptor are known, how they integrate to mediate development has remained unclear. Herein, we report that pr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057509/ https://ncbi.nlm.nih.gov/pubmed/19734904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1785 |
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