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Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket
Epilepsy has been treated for centuries with herbal remedies, including leaves of the African shrub Mallotus oppositifolius, yet the underlying molecular mechanisms have remained unclear. Voltage-gated potassium channel isoforms KCNQ2–5, predominantly KCNQ2/3 heteromers, underlie the neuronal M-curr...
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| Publicado no: | Nat Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155021/ https://ncbi.nlm.nih.gov/pubmed/30242262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06339-2 |
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