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M-Channel Activation Contributes to the Anticonvulsant Action of the Ketone Body β-Hydroxybutyrate
Ketogenic diets are effective therapies for refractory epilepsy, yet the underlying mechanisms are incompletely understood. The anticonvulsant efficacy of ketogenic diets correlates positively to the serum concentration of β-hydroxybutyrate (BHB), the primary ketone body generated by ketosis. Voltag...
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| Publié dans: | J Pharmacol Exp Ther |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6994816/ https://ncbi.nlm.nih.gov/pubmed/31757819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.263350 |
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