In Vitro Activity of LYS228, a Novel Monobactam Antibiotic, against Multidrug-Resistant Enterobacteriaceae

LYS228 is a novel monobactam with potent activity against Enterobacteriaceae. LYS228 is stable to metallo-β-lactamases (MBLs) and serine carbapenemases, including Klebsiella pneumoniae carbapenemases (KPCs), resulting in potency against the majority of extended-spectrum β-lactamase (ESBL)-producing...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Blais, Johanne, Lopez, Sara, Li, Cindy, Ruzin, Alexey, Ranjitkar, Srijan, Dean, Charles R., Leeds, Jennifer A., Casarez, Anthony, Simmons, Robert L., Reck, Folkert
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153794/
https://ncbi.nlm.nih.gov/pubmed/30038040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00552-18
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