Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice

Bile acids (BAs) control metabolism and inflammation by interacting with several receptors. Here, we report that intravenous infusion of taurodeoxycholate (TDCA) decreases serum pro-inflammatory cytokines, normalizes hypotension, protects against renal injury, and prolongs mouse survival during seps...

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Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Chang, Sooghee, Kim, Youn-Hee, Kim, Young-Joo, Kim, Young-Woo, Moon, Sungyoon, Lee, Yong Yook, Jung, Jin Sun, Kim, Youngsoo, Jung, Hi-Eun, Kim, Tae-Joo, Cheong, Taek-Chin, Moon, Hye-Jung, Cho, Jung-Ah, Kim, Hang-Rae, Han, Dohyun, Na, Yirang, Seok, Seung-Hyeok, Cho, Nam-Hyuk, Lee, Hai-Chon, Nam, Eun-Hee, Cho, Hyosuk, Choi, Murim, Minato, Nagahiro, Seong, Seung-Yong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153344/
https://ncbi.nlm.nih.gov/pubmed/30279688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01984
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