Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry

The heterotrimeric enzyme AMP-activated protein kinase (AMPK) is a major metabolic factor that regulates the homeostasis of cellular energy. In particular, AMPK mediates the insulin resistance that is associated with type 2 diabetes. Generally, cellular processes require tight regulation of protein...

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Bibliografiske detaljer
Main Authors: Moon, Sungyoon, Han, Dohyun, Kim, Yikwon, Jin, Jonghwa, Ho, Won-Kyung, Kim, Youngsoo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953747/
https://ncbi.nlm.nih.gov/pubmed/24625528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04376
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