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Mapping differential interactomes by affinity purification coupled with data independent mass spectrometry acquisition

Characterizing changes in protein-protein interactions associated with sequence variants (e.g. disease-associated mutations or splice forms) or following exposure to drugs, growth factors or hormones is critical to understanding how protein complexes are built, localized and regulated. Affinity puri...

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Detalhes bibliográficos
Main Authors: Lambert, Jean-Philippe, Ivosev, Gordana, Couzens, Amber L., Larsen, Brett, Taipale, Mikko, Lin, Zhen-Yuan, Zhong, Quan, Lindquist, Susan, Vidal, Marc, Aebersold, Ruedi, Pawson, Tony, Bonner, Ron, Tate, Stephen, Gingras, Anne-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882083/
https://ncbi.nlm.nih.gov/pubmed/24162924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2702
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