Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis

Most proteomic studies use liquid chromatography coupled to tandem mass spectrometry to identify and quantify the peptides generated by the proteolysis of a biological sample. However, with the current methods it remains challenging to rapidly, consistently, reproducibly, accurately, and sensitively...

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Bibliografiske detaljer
Main Authors: Gillet, Ludovic C., Navarro, Pedro, Tate, Stephen, Röst, Hannes, Selevsek, Nathalie, Reiter, Lukas, Bonner, Ron, Aebersold, Ruedi
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433915/
https://ncbi.nlm.nih.gov/pubmed/22261725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O111.016717
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