Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice

Bile acids (BAs) control metabolism and inflammation by interacting with several receptors. Here, we report that intravenous infusion of taurodeoxycholate (TDCA) decreases serum pro-inflammatory cytokines, normalizes hypotension, protects against renal injury, and prolongs mouse survival during seps...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Chang, Sooghee, Kim, Youn-Hee, Kim, Young-Joo, Kim, Young-Woo, Moon, Sungyoon, Lee, Yong Yook, Jung, Jin Sun, Kim, Youngsoo, Jung, Hi-Eun, Kim, Tae-Joo, Cheong, Taek-Chin, Moon, Hye-Jung, Cho, Jung-Ah, Kim, Hang-Rae, Han, Dohyun, Na, Yirang, Seok, Seung-Hyeok, Cho, Nam-Hyuk, Lee, Hai-Chon, Nam, Eun-Hee, Cho, Hyosuk, Choi, Murim, Minato, Nagahiro, Seong, Seung-Yong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153344/
https://ncbi.nlm.nih.gov/pubmed/30279688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01984
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