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Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice

Bile acids (BAs) control metabolism and inflammation by interacting with several receptors. Here, we report that intravenous infusion of taurodeoxycholate (TDCA) decreases serum pro-inflammatory cytokines, normalizes hypotension, protects against renal injury, and prolongs mouse survival during seps...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Chang, Sooghee, Kim, Youn-Hee, Kim, Young-Joo, Kim, Young-Woo, Moon, Sungyoon, Lee, Yong Yook, Jung, Jin Sun, Kim, Youngsoo, Jung, Hi-Eun, Kim, Tae-Joo, Cheong, Taek-Chin, Moon, Hye-Jung, Cho, Jung-Ah, Kim, Hang-Rae, Han, Dohyun, Na, Yirang, Seok, Seung-Hyeok, Cho, Nam-Hyuk, Lee, Hai-Chon, Nam, Eun-Hee, Cho, Hyosuk, Choi, Murim, Minato, Nagahiro, Seong, Seung-Yong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153344/
https://ncbi.nlm.nih.gov/pubmed/30279688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01984
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