Inhibition of DNA Methylation With Zebularine Alters Lipopolysaccharide-Induced Sickness Behavior and Neuroinflammation in Mice

Activity of DNA methyltransferases (DNMTs), the enzymes that catalyze DNA methylation, is dynamically regulated in the brain. DNMT inhibitors alter DNA methylation globally in the brain and at individual neural plasticity-associated genes, but how DNMT inhibitors centrally influence lipopolysacchari...

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Detaylı Bibliyografya
Yayımlandı:Front Neurosci
Asıl Yazarlar: Matt, Stephanie M., Zimmerman, Jalisa D., Lawson, Marcus A., Bustamante, Angela C., Uddin, Monica, Johnson, Rodney W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Neuroscience
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153314/
https://ncbi.nlm.nih.gov/pubmed/30279646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00636
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