Effect of BDNFVal66Met on disease markers in dominantly inherited AD

OBJECTIVE. Previous studies suggest that the brain-derived neurotrophic factor (BDNF) Val66Met (rs6265) polymorphism may influence symptom onset in Alzheimer’s disease (AD). Our recent cross-sectional findings suggest that Met66 may influence clinical expression in dominantly inherited AD (DIAD) thr...

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Publicat a:Ann Neurol
Autors principals: Lim, Yen Ying, Hassenstab, Jason, Goate, Alison, Fagan, Anne M., Benzinger, Tammie L.S., Cruchaga, Carlos, McDade, Eric, Chhatwal, Jasmeer, Levin, Johannes, Farlow, Martin R., GraffRadford, Neill R., Laske, Christoph, Masters, Colin L, Salloway, Stephen, Schofield, Peter, Morris, John C., Maruff, Paul, Bateman, Randall J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153076/
https://ncbi.nlm.nih.gov/pubmed/30014553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25299
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