Effect of BDNFVal66Met on disease markers in dominantly inherited AD

OBJECTIVE. Previous studies suggest that the brain-derived neurotrophic factor (BDNF) Val66Met (rs6265) polymorphism may influence symptom onset in Alzheimer’s disease (AD). Our recent cross-sectional findings suggest that Met66 may influence clinical expression in dominantly inherited AD (DIAD) thr...

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Pubblicato in:Ann Neurol
Autori principali: Lim, Yen Ying, Hassenstab, Jason, Goate, Alison, Fagan, Anne M., Benzinger, Tammie L.S., Cruchaga, Carlos, McDade, Eric, Chhatwal, Jasmeer, Levin, Johannes, Farlow, Martin R., GraffRadford, Neill R., Laske, Christoph, Masters, Colin L, Salloway, Stephen, Schofield, Peter, Morris, John C., Maruff, Paul, Bateman, Randall J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153076/
https://ncbi.nlm.nih.gov/pubmed/30014553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25299
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