Effect of BDNFVal66Met on disease markers in dominantly inherited AD

OBJECTIVE. Previous studies suggest that the brain-derived neurotrophic factor (BDNF) Val66Met (rs6265) polymorphism may influence symptom onset in Alzheimer’s disease (AD). Our recent cross-sectional findings suggest that Met66 may influence clinical expression in dominantly inherited AD (DIAD) thr...

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Publicado en:Ann Neurol
Main Authors: Lim, Yen Ying, Hassenstab, Jason, Goate, Alison, Fagan, Anne M., Benzinger, Tammie L.S., Cruchaga, Carlos, McDade, Eric, Chhatwal, Jasmeer, Levin, Johannes, Farlow, Martin R., GraffRadford, Neill R., Laske, Christoph, Masters, Colin L, Salloway, Stephen, Schofield, Peter, Morris, John C., Maruff, Paul, Bateman, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153076/
https://ncbi.nlm.nih.gov/pubmed/30014553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25299
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