BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease

See Rogaeva and Schmitt-Ulms (doi: 10.1093/aww201 ) for a scientific commentary on this article . The brain-derived neurotrophic factor ( BDNF ) Val66Met polymorphism is implicated in synaptic excitation and neuronal integrity, and has previously been shown to moderate amyloid-β-related memory decli...

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Publicado no:Brain
Main Authors: Lim, Yen Ying, Hassenstab, Jason, Cruchaga, Carlos, Goate, Alison, Fagan, Anne M., Benzinger, Tammie L. S., Maruff, Paul, Snyder, Peter J., Masters, Colin L., Allegri, Ricardo, Chhatwal, Jasmeer, Farlow, Martin R., Graff-Radford, Neill R., Laske, Christoph, Levin, Johannes, McDade, Eric, Ringman, John M., Rossor, Martin, Salloway, Stephen, Schofield, Peter R., Holtzman, David M., Morris, John C., Bateman, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815565/
https://ncbi.nlm.nih.gov/pubmed/27521573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww200
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