BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease

See Rogaeva and Schmitt-Ulms (doi: 10.1093/aww201 ) for a scientific commentary on this article . The brain-derived neurotrophic factor ( BDNF ) Val66Met polymorphism is implicated in synaptic excitation and neuronal integrity, and has previously been shown to moderate amyloid-β-related memory decli...

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Bibliografiska uppgifter
I publikationen:Brain
Huvudupphovsmän: Lim, Yen Ying, Hassenstab, Jason, Cruchaga, Carlos, Goate, Alison, Fagan, Anne M., Benzinger, Tammie L. S., Maruff, Paul, Snyder, Peter J., Masters, Colin L., Allegri, Ricardo, Chhatwal, Jasmeer, Farlow, Martin R., Graff-Radford, Neill R., Laske, Christoph, Levin, Johannes, McDade, Eric, Ringman, John M., Rossor, Martin, Salloway, Stephen, Schofield, Peter R., Holtzman, David M., Morris, John C., Bateman, Randall J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2016
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815565/
https://ncbi.nlm.nih.gov/pubmed/27521573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww200
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