Effect of BDNFVal66Met on disease markers in dominantly inherited AD

OBJECTIVE. Previous studies suggest that the brain-derived neurotrophic factor (BDNF) Val66Met (rs6265) polymorphism may influence symptom onset in Alzheimer’s disease (AD). Our recent cross-sectional findings suggest that Met66 may influence clinical expression in dominantly inherited AD (DIAD) thr...

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Bibliografske podrobnosti
izdano v:Ann Neurol
Main Authors: Lim, Yen Ying, Hassenstab, Jason, Goate, Alison, Fagan, Anne M., Benzinger, Tammie L.S., Cruchaga, Carlos, McDade, Eric, Chhatwal, Jasmeer, Levin, Johannes, Farlow, Martin R., GraffRadford, Neill R., Laske, Christoph, Masters, Colin L, Salloway, Stephen, Schofield, Peter, Morris, John C., Maruff, Paul, Bateman, Randall J.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153076/
https://ncbi.nlm.nih.gov/pubmed/30014553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25299
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