Staging Biomarkers in Preclinical Autosomal Dominant Alzheimer Disease by Estimated Years to Symptom Onset

INTRODUCTION: Staging preclinical Alzheimer disease (AD) by the expected years to symptom onset (EYO) in autosomal dominant AD (ADAD) through biomarker correlations is important. METHODS: We estimated the correlation matrix between EYO/cognition and imaging/CSF biomarkers, and searched for the EYO c...

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Published in:Alzheimers Dement
Main Authors: Wang, Guoqiao, Coble, Dean, McDade, Eric M., Hassenstab, Jason, Fagan, Anne M., Benzinger, Tammie L.S., Bateman, Randall J., Morris, John C., Xiong, Chengjie
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461496/
https://ncbi.nlm.nih.gov/pubmed/30773445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.12.008
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