Improved Ribo-seq enables identification of cryptic translation events

Ribosome profiling has predicted thousands of short open reading frames (sORFs) in eukaryotic cells, but still suffers from substantial levels of noise. PRICE (https://github.com/erhard-lab/price) is a computational method modeling the experimental noise to accurately resolve overlapping sORFs and n...

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Bibliographic Details
Published in:Nat Methods
Main Authors: Erhard, Florian, Halenius, Anne, Zimmermann, Cosima, L’Hernault, Anne, Kowalewski, Daniel J., Weekes, Michael P., Stevanovic, Stefan, Zimmer, Ralf, Dölken, Lars
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152898/
https://ncbi.nlm.nih.gov/pubmed/29529017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4631
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