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Improved Ribo-seq enables identification of cryptic translation events

Ribosome profiling has predicted thousands of short open reading frames (sORFs) in eukaryotic cells, but still suffers from substantial levels of noise. PRICE (https://github.com/erhard-lab/price) is a computational method modeling the experimental noise to accurately resolve overlapping sORFs and n...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Erhard, Florian, Halenius, Anne, Zimmermann, Cosima, L’Hernault, Anne, Kowalewski, Daniel J., Weekes, Michael P., Stevanovic, Stefan, Zimmer, Ralf, Dölken, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152898/
https://ncbi.nlm.nih.gov/pubmed/29529017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4631
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