Improved Ribo-seq enables identification of cryptic translation events

Ribosome profiling has predicted thousands of short open reading frames (sORFs) in eukaryotic cells, but still suffers from substantial levels of noise. PRICE (https://github.com/erhard-lab/price) is a computational method modeling the experimental noise to accurately resolve overlapping sORFs and n...

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Bibliografiske detaljer
Udgivet i:Nat Methods
Main Authors: Erhard, Florian, Halenius, Anne, Zimmermann, Cosima, L’Hernault, Anne, Kowalewski, Daniel J., Weekes, Michael P., Stevanovic, Stefan, Zimmer, Ralf, Dölken, Lars
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152898/
https://ncbi.nlm.nih.gov/pubmed/29529017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4631
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