Widespread disruption of host transcription termination in HSV-1 infection

Herpes simplex virus 1 (HSV-1) is an important human pathogen and a paradigm for virus-induced host shut-off. Here we show that global changes in transcription and RNA processing and their impact on translation can be analysed in a single experimental setting by applying 4sU-tagging of newly transcr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rutkowski, Andrzej J., Erhard, Florian, L'Hernault, Anne, Bonfert, Thomas, Schilhabel, Markus, Crump, Colin, Rosenstiel, Philip, Efstathiou, Stacey, Zimmer, Ralf, Friedel, Caroline C., Dölken, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441252/
https://ncbi.nlm.nih.gov/pubmed/25989971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8126
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