PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5

Macroautophagy is induced under various stresses to remove cytotoxic materials, including misfolded proteins and their aggregates. These protein cargoes are collected by specific autophagic receptors such as SQSTM1/p62 (sequestosome 1) and delivered to phagophores for lysosomal degradation. To date,...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Autophagy
Hlavní autoři: Lee, Dae-Hee, Kim, Daeho, Kim, Sung Tae, Jeong, Soyeon, Kim, Jung Lim, Shim, Sang Mi, Heo, Ah Jung, Song, Xinxin, Guo, Zong Sheng, Bartlett, David L., Oh, Sang Cheul, Lee, Junho, Saito, Yoshiro, Kim, Bo Yeon, Kwon, Yong Tae, Lee, Yong J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152518/
https://ncbi.nlm.nih.gov/pubmed/29976090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1491212
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky