Regulation of autophagic proteolysis by the N-recognin SQSTM1/p62 of the N-end rule pathway

In macroautophagy/autophagy, cargoes are collected by specific receptors, such as SQSTM1/p62 (sequestosome 1), and delivered to phagophores for lysosomal degradation. To date, little is known about how cells modulate SQSTM1 activity and autophagosome biogenesis in response to accumulating cargoes. I...

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Vydáno v:Autophagy
Hlavní autoři: Cha-Molstad, Hyunjoo, Lee, Su Hyun, Kim, Jung Gi, Sung, Ki Woon, Hwang, Joonsung, Shim, Sang Mi, Ganipisetti, Srinivasrao, McGuire, Terry, Mook-Jung, Inhee, Ciechanover, Aaron, Xie, Xiang-Qun, Kim, Bo Yeon, Kwon, Yong Tae
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Autophagic Puncta
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902234/
https://ncbi.nlm.nih.gov/pubmed/29261001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1415190
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