Codon misreading tRNAs promote tumor growth in mice

Deregulation of tRNAs, aminoacyl-tRNA synthetases and tRNA modifying enzymes are common in cancer, raising the hypothesis that protein synthesis efficiency and accuracy (mistranslation) are compromised in tumors. We show here that human colon tumors and xenograft tumors produced in mice by two epith...

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Vydáno v:RNA Biol
Hlavní autoři: Santos, Mafalda, Pereira, Patricia M., Varanda, A. Sofia, Carvalho, Joana, Azevedo, Mafalda, Mateus, Denisa D., Mendes, Nuno, Oliveira, Patricia, Trindade, Fábio, Pinto, Marta Teixeira, Bordeira-Carriço, Renata, Carneiro, Fátima, Vitorino, Rui, Oliveira, Carla, Santos, Manuel A. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152441/
https://ncbi.nlm.nih.gov/pubmed/29558247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1454244
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