Codon misreading tRNAs promote tumor growth in mice

Deregulation of tRNAs, aminoacyl-tRNA synthetases and tRNA modifying enzymes are common in cancer, raising the hypothesis that protein synthesis efficiency and accuracy (mistranslation) are compromised in tumors. We show here that human colon tumors and xenograft tumors produced in mice by two epith...

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Dettagli Bibliografici
Pubblicato in:RNA Biol
Autori principali: Santos, Mafalda, Pereira, Patricia M., Varanda, A. Sofia, Carvalho, Joana, Azevedo, Mafalda, Mateus, Denisa D., Mendes, Nuno, Oliveira, Patricia, Trindade, Fábio, Pinto, Marta Teixeira, Bordeira-Carriço, Renata, Carneiro, Fátima, Vitorino, Rui, Oliveira, Carla, Santos, Manuel A. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152441/
https://ncbi.nlm.nih.gov/pubmed/29558247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1454244
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