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Codon misreading tRNAs promote tumor growth in mice
Deregulation of tRNAs, aminoacyl-tRNA synthetases and tRNA modifying enzymes are common in cancer, raising the hypothesis that protein synthesis efficiency and accuracy (mistranslation) are compromised in tumors. We show here that human colon tumors and xenograft tumors produced in mice by two epith...
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| Pubblicato in: | RNA Biol |
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| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152441/ https://ncbi.nlm.nih.gov/pubmed/29558247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1454244 |
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