Codon misreading tRNAs promote tumor growth in mice

Deregulation of tRNAs, aminoacyl-tRNA synthetases and tRNA modifying enzymes are common in cancer, raising the hypothesis that protein synthesis efficiency and accuracy (mistranslation) are compromised in tumors. We show here that human colon tumors and xenograft tumors produced in mice by two epith...

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Bibliographic Details
Published in:RNA Biol
Main Authors: Santos, Mafalda, Pereira, Patricia M., Varanda, A. Sofia, Carvalho, Joana, Azevedo, Mafalda, Mateus, Denisa D., Mendes, Nuno, Oliveira, Patricia, Trindade, Fábio, Pinto, Marta Teixeira, Bordeira-Carriço, Renata, Carneiro, Fátima, Vitorino, Rui, Oliveira, Carla, Santos, Manuel A. S.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152441/
https://ncbi.nlm.nih.gov/pubmed/29558247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1454244
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