Codon misreading tRNAs promote tumor growth in mice

Deregulation of tRNAs, aminoacyl-tRNA synthetases and tRNA modifying enzymes are common in cancer, raising the hypothesis that protein synthesis efficiency and accuracy (mistranslation) are compromised in tumors. We show here that human colon tumors and xenograft tumors produced in mice by two epith...

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Enregistré dans:
Détails bibliographiques
Publié dans:RNA Biol
Auteurs principaux: Santos, Mafalda, Pereira, Patricia M., Varanda, A. Sofia, Carvalho, Joana, Azevedo, Mafalda, Mateus, Denisa D., Mendes, Nuno, Oliveira, Patricia, Trindade, Fábio, Pinto, Marta Teixeira, Bordeira-Carriço, Renata, Carneiro, Fátima, Vitorino, Rui, Oliveira, Carla, Santos, Manuel A. S.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152441/
https://ncbi.nlm.nih.gov/pubmed/29558247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1454244
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