3-Bromopyruvate sensitizes human breast cancer cells to TRAIL-induced apoptosis via the phosphorylated AMPK-mediated upregulation of DR5

Previous studies have indicated that the sensitivity of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis is associated with the expression of death receptors on the cell membrane. However, drug resistance limits the use of TRAIL in cancer thera...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Chen, Yuzhong, Wei, Li, Zhang, Xiaojing, Liu, Xianfu, Chen, Yansong, Zhang, Song, Zhou, Lanzhu, Li, Qixiang, Pan, Qiong, Zhao, Surong, Liu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151892/
https://ncbi.nlm.nih.gov/pubmed/30132536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2018.6644
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