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Improving anticancer activity towards colon cancer cells with a new p53‐activating agent

BACKGROUND AND PURPOSE: Impairment of the tumour suppressor p53 pathway is a major event in human cancers, making p53 activation one of the most attractive therapeutic strategies to halt cancer. Here, we have identified a new selective p53 activator and investigated its potential as an anticancer ag...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Raimundo, Liliana, Espadinha, Margarida, Soares, Joana, Loureiro, Joana B, Alves, Marco G, Santos, Maria M M, Saraiva, Lucília
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151341/
https://ncbi.nlm.nih.gov/pubmed/30076608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14468
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