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Three-Dimensional Analysis of the Interactions between hLDH5 and Its Inhibitors
Inhibitors of human lactate dehydrogenase (hLDH5)—the enzyme responsible for the conversion of pyruvate to lactate coupled with oxidation of NADH to NAD(+)—are promising therapeutic agents against cancer because this enzyme is generally found to be overexpressed in most invasive cancer cells and is...
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| Izdano u: | Molecules |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6149858/ https://ncbi.nlm.nih.gov/pubmed/29236080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22122217 |
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