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Small-molecule inhibitors of human LDH5

The latest findings on the role played by human LDH5 (hLDH5) in the promotion of glycolysis in invasive tumor cells indicates that this enzyme subtype is a promising therapeutic target for invasive cancer. Compounds able to selectively inhibit hLDH5 hold promise for the cure of neoplastic diseases....

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Detalhes bibliográficos
Main Authors: Granchi, Carlotta, Paterni, Ilaria, Rani, Reshma, Minutolo, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952072/
https://ncbi.nlm.nih.gov/pubmed/24175747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.151
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