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Absence of rapid selection for acyclovir or penciclovir resistance following suboptimal oral prodrug therapy of HSV-infected mice

BACKGROUND: Acyclovir (ACV) resistant herpes simplex virus (HSV) isolates can be readily selected in animal infection models receiving suboptimal ACV treatment, however no comparative studies of the emergence of resistance following suboptimal treatment with valacyclovir (VCV) or famciclovir (FCV),...

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Autori principali: Sarisky, Robert T, Bartus, H Ron, Dennis, Shelley A, Quail, Matthew R, Nguyen, Tammy T, Wittrock, Robert J, Halsey, Wendy S, Bacon, Teresa H, Leary, Jeffry J, Sutton, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC61449/
https://ncbi.nlm.nih.gov/pubmed/11749671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-1-24
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