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Absence of rapid selection for acyclovir or penciclovir resistance following suboptimal oral prodrug therapy of HSV-infected mice

BACKGROUND: Acyclovir (ACV) resistant herpes simplex virus (HSV) isolates can be readily selected in animal infection models receiving suboptimal ACV treatment, however no comparative studies of the emergence of resistance following suboptimal treatment with valacyclovir (VCV) or famciclovir (FCV),...

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Библиографические подробности
Главные авторы: Sarisky, Robert T, Bartus, H Ron, Dennis, Shelley A, Quail, Matthew R, Nguyen, Tammy T, Wittrock, Robert J, Halsey, Wendy S, Bacon, Teresa H, Leary, Jeffry J, Sutton, David
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC61449/
https://ncbi.nlm.nih.gov/pubmed/11749671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-1-24
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