Absence of rapid selection for acyclovir or penciclovir resistance following suboptimal oral prodrug therapy of HSV-infected mice

BACKGROUND: Acyclovir (ACV) resistant herpes simplex virus (HSV) isolates can be readily selected in animal infection models receiving suboptimal ACV treatment, however no comparative studies of the emergence of resistance following suboptimal treatment with valacyclovir (VCV) or famciclovir (FCV),...

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Detalhes bibliográficos
Main Authors: Sarisky, Robert T, Bartus, H Ron, Dennis, Shelley A, Quail, Matthew R, Nguyen, Tammy T, Wittrock, Robert J, Halsey, Wendy S, Bacon, Teresa H, Leary, Jeffry J, Sutton, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC61449/
https://ncbi.nlm.nih.gov/pubmed/11749671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-1-24
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