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Absence of rapid selection for acyclovir or penciclovir resistance following suboptimal oral prodrug therapy of HSV-infected mice

BACKGROUND: Acyclovir (ACV) resistant herpes simplex virus (HSV) isolates can be readily selected in animal infection models receiving suboptimal ACV treatment, however no comparative studies of the emergence of resistance following suboptimal treatment with valacyclovir (VCV) or famciclovir (FCV),...

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Publicado en:BMC Infect Dis
Principais autores: Sarisky, Robert T, Bartus, H Ron, Dennis, Shelley A, Quail, Matthew R, Nguyen, Tammy T, Wittrock, Robert J, Halsey, Wendy S, Bacon, Teresa H, Leary, Jeffry J, Sutton, David
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2001
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11749671/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2334-1-24
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